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Drug-Induced Parkinsonism? Trimetazidine is widely used in angina pectoris and in ischemia. of neurosensorial tissues as in Mnie`res disease.. That kind of metabolic therapy, they said, is offered by trimetazidine, an old antiischemic drug that comes in a new modified release formulation (Vastarel. Anti-ischaemic efficacy and tolerability of trimetazidine in elderly patients with angina. Clin Drug Invest 2000; 19:
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Myocardial metabolic manipulation using drugs such as trimetazidine may offer.. The antianginal drug trimetazidine shifts cardiac energy metabolism from. As a consequence, intrusion of water towards the tablet matrix and diffusion of drug are slowed down, allowing a controlled slow release of the drug.. Thus, drug dosages in older patients have to be chosen with great care and. antianginal
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